Title : Triterpenes from Alisma orientalis act as androgen receptor agonists, progesterone receptor antagonists, and glucocorticoid receptor antagonists.

Pub. Date : 2014 Aug 1

PMID : 24915879






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Indeed, in the transient transfection reporter assays, alisol M 23-acetate and alisol A 23-acetate transactivated AR in dose-dependent manner, while they transrepressed the transactivation effects exerted by agonist-activated PR and GR. alisol B monoacetate nuclear receptor subfamily 3 group C member 1 Homo sapiens
2 All these results indicate that alisol M 23-acetate and alisol A 23-acetate from Alisma orientalis might possess therapeutic effects through their modulation of AR, PR, and GR pathways. alisol B monoacetate nuclear receptor subfamily 3 group C member 1 Homo sapiens