Title : The potentiation of the antitumor activity but not toxicity of bleomycin by 3-aminobenzamide.

Pub. Date : 1989 Dec

PMID : 2482841






2 Functional Relationships(s)
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1 Our previous studies have demonstrated that 3-aminobenzamide (3AB), an inhibitor of adenosine diphosphate-ribosyl transferase (ADPRT) could enhance the cytotoxicity (in vitro) and antitumor activity (in vivo) of bleomycin (BLM) A5 and peplomycin (PEP) against S-180, hepatoma and Ehrlich ascites carcinoma (EAC). 3-aminobenzamide ADP-ribosyltransferase 1 Mus musculus
2 Our previous studies have demonstrated that 3-aminobenzamide (3AB), an inhibitor of adenosine diphosphate-ribosyl transferase (ADPRT) could enhance the cytotoxicity (in vitro) and antitumor activity (in vivo) of bleomycin (BLM) A5 and peplomycin (PEP) against S-180, hepatoma and Ehrlich ascites carcinoma (EAC). 3-aminobenzamide ADP-ribosyltransferase 1 Mus musculus