Title : Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.

Pub. Date : 2014 Oct 1

PMID : 24668417






1 Functional Relationships(s)
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1 Previous studies in rats have demonstrated that microsomal prostaglandin E synthase-1 (mPGES-1) is induced in brain vascular cells that also express inducible cyclooxygenase-2, suggesting that such cells are the source of the increased PGE2 levels that are seen in the brain following peripheral immune stimulation, and that are associated with sickness responses such as fever, anorexia, and stress hormone release. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus