Title : A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency.

Pub. Date : 2014 Jun

PMID : 24611904

1 Functional Relationships(s)
Compound Name
Protein Name
1 Based on recent evidence that XIAP is essential for nucleotide-binding and oligomerization domains (NOD)1/2 signalling, we evaluated the use of a simple flow cytometric assay assessing tumour necrosis factor (TNF) production of monocytes in response to NOD2 stimulation by muramyl dipeptides (L18-MDP) for the functional diagnosis of XIAP deficiency. Dipeptides tumor necrosis factor Homo sapiens