Pub. Date : 2014 Apr
PMID : 24493699
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CONCLUSIONS: Loss of Casq2 increases risk of AF by promoting regional SCaEs and delayed afterdepolarizations in atrial tissue, which can be prevented by RyR2 inhibition with R-propafenone. | Propafenone | ryanodine receptor 2, cardiac | Mus musculus |
| 2 | Targeting AF caused by leaky RyR2 Ca channels with R-propafenone may be a more mechanism-based approach to treating this common arrhythmia. | Propafenone | ryanodine receptor 2, cardiac | Mus musculus |