Title : Thrombin inhibitory activity of heparin cofactor II depends on the molecular weight and sulfate amount of dextran sulfate.

Pub. Date : 1986 Nov 1

PMID : 2432675






1 Functional Relationships(s)
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1 The maximum second order rate constant of heparin cofactor II-thrombin reaction in the presence of the fractions of over-10 kDa and 18% sulfur was 2.7 X 10(8) M-1 min-1 that was almost same as in the presence of heparin or dermatan sulfate. Dermatan Sulfate CD59 molecule (CD59 blood group) Homo sapiens