Title : Extracellular NAD(+) inhibits human neutrophil apoptosis.

Pub. Date : 2014 Apr

PMID : 24292505






1 Functional Relationships(s)
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1 Extracellular NAD(+) inhibited proteasome-dependent degradation of Mcl-1 upstream of caspase activation and, furthermore, suppressed Bax translocation to the mitochondria and attenuated both dissipation of mitochondrial transmembrane potential (DeltaPsim) and cytochrome c release from the mitochondria into the cytosol. NAD cytochrome c, somatic Homo sapiens