Title : CAGn repeat of the androgen receptor is linked to proopiomelanocortin promoter methylation-relevance for craving of male alcohol-dependent patients?

Pub. Date : 2014 May

PMID : 24271034






4 Functional Relationships(s)
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1 CAGn repeat of the androgen receptor is linked to proopiomelanocortin promoter methylation-relevance for craving of male alcohol-dependent patients? Alcohols proopiomelanocortin Homo sapiens
2 RATIONALE: Previous findings of the Franconian Alcoholism Research Studies showed that both the CAGn of the androgen receptor (AR) and the promoter methylation of the hypothalamic peptide proopiomelanocortin (POMC) were associated with craving of male alcohol-dependent patients. Alcohols proopiomelanocortin Homo sapiens
3 RATIONALE: Previous findings of the Franconian Alcoholism Research Studies showed that both the CAGn of the androgen receptor (AR) and the promoter methylation of the hypothalamic peptide proopiomelanocortin (POMC) were associated with craving of male alcohol-dependent patients. Alcohols proopiomelanocortin Homo sapiens
4 CONCLUSIONS: This work shows that the AR and the POMC gene might functionally interact with each other and subsequently mediate craving in alcohol-dependent patients. Alcohols proopiomelanocortin Homo sapiens