Title : Bisubstrate UDP-peptide conjugates as human O-GlcNAc transferase inhibitors.

Pub. Date : 2014 Feb 1

PMID : 24256146






1 Functional Relationships(s)
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1 We report OGT bisubstrate-linked inhibitors (goblins) in which the acceptor serine in the peptide VTPVSTA is covalently linked to UDP, eliminating the GlcNAc pyranoside ring. pyranoside O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens