Title : The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.

Pub. Date : 2014 Oct

PMID : 24176765

1 Functional Relationships(s)
Compound Name
Protein Name
1 The placenta, adrenal glands and epidermal keratinocytes have been shown to metabolize vitamin D3 via this CYP11A1-mediated pathway that is modified by the activity of CYP27B1, with 20(OH)D3 (the major metabolite), 20,23(OH)2D3, 1,20(OH)2D3, 1,20,23(OH)3D3 and 17,20,23(OH)3D3 being detected, defining these secosteroids as endogenous regulators/natural products. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens