Title : An EGFR/CD13 bispecific fusion protein and its enediyne-energized analog show potent antitumor activity.

Pub. Date : 2014 Jan

PMID : 24100279






1 Functional Relationships(s)
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1 Determined by the MTT assay, the bispecific, enediyne-energized ER(Fv)-LDP-NGR-AE showed highly potent cytotoxicity to EGFR/CD13-overexpressed MCF-7 cells, with an IC50 value of 3.4x10 mol/l, whereas for the EGFR-overexpressed A431 cells, the IC50 value was 2.2x10 mol/l. monooxyethylene trimethylolpropane tristearate carboxypeptidase Q Homo sapiens