Title : Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs.

Pub. Date : 2013 Dec

PMID : 24095863






3 Functional Relationships(s)
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Protein Name
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1 In Caco-2 and HCT-8 nicotine reverted 5-FU and CPT apoptotic effects through AKT phosphorylation, as demonstrated by apoptotic increase in presence of LY294002, an AKT phosphorylation inhibitor. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 In Caco-2 and HCT-8 nicotine reverted 5-FU and CPT apoptotic effects through AKT phosphorylation, as demonstrated by apoptotic increase in presence of LY294002, an AKT phosphorylation inhibitor. Nicotine AKT serine/threonine kinase 1 Homo sapiens
3 Nicotine anti-apoptotic effects were exerted through ERK and AKT pathway activation. Nicotine AKT serine/threonine kinase 1 Homo sapiens