Title : A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation.

Pub. Date : 1990 Jan 26

PMID : 2405486






1 Functional Relationships(s)
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1 Moreover, 10 micromolar concentrations of U-81749 significantly inhibited proteolysis of the HIV-1 gag polyprotein (p55) to the mature viral structural proteins p24 and p17 in cells infected with a recombinant vaccinia virus expressing the HIV-1 gag-pol genes. U 81749 H3 histone pseudogene 44 Homo sapiens