Title : Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer.

Pub. Date : 2013 Nov 15

PMID : 24016618






3 Functional Relationships(s)
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1 We hypothesized that pretreatment with mifepristone, a GR antagonist, would potentiate the efficacy of chemotherapy in GR+ TNBCs by inhibiting the antiapoptotic signaling pathways of GR and increasing the cytotoxic efficiency of chemotherapy. tnbcs nuclear receptor subfamily 3, group C, member 1 Mus musculus
2 We hypothesized that pretreatment with mifepristone, a GR antagonist, would potentiate the efficacy of chemotherapy in GR+ TNBCs by inhibiting the antiapoptotic signaling pathways of GR and increasing the cytotoxic efficiency of chemotherapy. tnbcs nuclear receptor subfamily 3, group C, member 1 Mus musculus
3 We hypothesized that pretreatment with mifepristone, a GR antagonist, would potentiate the efficacy of chemotherapy in GR+ TNBCs by inhibiting the antiapoptotic signaling pathways of GR and increasing the cytotoxic efficiency of chemotherapy. tnbcs nuclear receptor subfamily 3, group C, member 1 Mus musculus