Title : The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.

Pub. Date : 2013 Sep 3

PMID : 24011070

1 Functional Relationships(s)
Compound Name
Protein Name
1 Taken together, our data suggest a mechanism whereby miR-199a~214 actively represses cardiac PPARdelta expression, facilitating a metabolic shift from predominant reliance on fatty acid utilization in the healthy myocardium toward increased reliance on glucose metabolism at the onset of heart failure. Glucose peroxisome proliferator activator receptor delta Mus musculus