Title : Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytes apoptosis.

Pub. Date : 2013

PMID : 23363563






2 Functional Relationships(s)
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1 CONCLUSION: Gen protects against the adverse cardiac effects of As2O3 partly by mitigating cardiomyocytes apoptosis induced by As2O3 through attenuating intracellular calcium overload and downregulating protein expression of p-JNK and pp38-MAPK to ameliorate the damage of Deltapsim leading to suppression of caspase-3 activation. Arsenic Trioxide caspase 3 Homo sapiens
2 CONCLUSION: Gen protects against the adverse cardiac effects of As2O3 partly by mitigating cardiomyocytes apoptosis induced by As2O3 through attenuating intracellular calcium overload and downregulating protein expression of p-JNK and pp38-MAPK to ameliorate the damage of Deltapsim leading to suppression of caspase-3 activation. Arsenic Trioxide caspase 3 Homo sapiens