Title : Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-κB activation for pancreatic cancer.

Pub. Date : 2013 Jun 1

PMID : 23348695






1 Functional Relationships(s)
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1 In combination treatment with nafamostat mesilate and oxaliplatin, NF-kappaB activation was inhibited by suppressing IkappaBalpha phosphorylation, and caspase-8-mediated apoptosis was more prominent than that treated with oxaliplatin alone, both in vitro and in vivo. nafamostat caspase 8 Homo sapiens