Title : Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia.

Pub. Date : 2013 Mar 10

PMID : 23279876






3 Functional Relationships(s)
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Protein Name
Organism
1 For insulin signaling transduction, phosphorylation of insulin receptor (IR), insulin receptor substrate-1 (IRS1) at the tyrosine residue, Akt, and AMP-activated protein kinase (AMPK), were attenuated in the liver, while negative regulators of insulin action, including phosphorylation of p38, c-Jun N-terminal kinase (JNK), and insulin receptor substrate-1 (IRS1) at the serine residue, were increased. Tyrosine insulin receptor substrate 1 Rattus norvegicus
2 For insulin signaling transduction, phosphorylation of insulin receptor (IR), insulin receptor substrate-1 (IRS1) at the tyrosine residue, Akt, and AMP-activated protein kinase (AMPK), were attenuated in the liver, while negative regulators of insulin action, including phosphorylation of p38, c-Jun N-terminal kinase (JNK), and insulin receptor substrate-1 (IRS1) at the serine residue, were increased. Tyrosine insulin receptor substrate 1 Rattus norvegicus
3 In addition, the brains of rats with stroke exhibited a reduction in phosphorylation of IRS1 at the tyrosine residue and Akt. Tyrosine insulin receptor substrate 1 Rattus norvegicus