Title : Thymoquinone induces apoptosis in malignant T-cells via generation of ROS.

Pub. Date : 2013 Jan 1

PMID : 23277025






1 Functional Relationships(s)
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1 A greater depletion of the antioxidant enzyme glutathione occurred in Jurkat, which consequently led to an increase in ROS, loss of mitochondrial membrane potential, cytochrome c release, activation of caspases 3 and 9, and cleavage of PARP. Glutathione caspase 3 Homo sapiens