Title : Thymoquinone induces apoptosis in malignant T-cells via generation of ROS.

Pub. Date : 2013 Jan 1

PMID : 23277025

1 Functional Relationships(s)
Compound Name
Protein Name
1 A greater depletion of the antioxidant enzyme glutathione occurred in Jurkat, which consequently led to an increase in ROS, loss of mitochondrial membrane potential, cytochrome c release, activation of caspases 3 and 9, and cleavage of PARP. Glutathione caspase 3 Homo sapiens