Title : Folic acid inhibits endothelial cell migration through inhibiting the RhoA activity mediated by activating the folic acid receptor/cSrc/p190RhoGAP-signaling pathway.

Pub. Date : 2013 Feb 1

PMID : 23178654

1 Functional Relationships(s)
Compound Name
Protein Name
1 Previously, our in vivo studies demonstrated that folic acid (FA) could inhibit angiogenesis and in vitro studies showed that FA reduced vascular endothelial cell proliferation through activating the cSrc/ERK-2/NFkappaB/p53 pathway mediated by FA receptor (FR). Folic Acid tumor protein p53 Homo sapiens