Title : On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different.

Pub. Date : 2012

PMID : 23152789






1 Functional Relationships(s)
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1 The availability of multiple co-crystal structures facilitates a structural analysis that challenges the long-held belief that the GAG binding sites in antithrombin and thrombin are essentially similar with high solvent exposure and shallow surface characteristics. Glycosaminoglycans serpin family C member 1 Homo sapiens