Title : Identification of two Legionella pneumophila effectors that manipulate host phospholipids biosynthesis.

Pub. Date : 2012

PMID : 23133385






1 Functional Relationships(s)
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1 In addition, by using relevant yeast genetic backgrounds we examined several L. pneumophila effectors expected to be involved in phospholipids biosynthesis and identified an effector (LpdA) that contains a phospholipase-D (PLD) domain which caused lethal effect only in a dgk1 deletion mutant of yeast. lpda diacylglycerol kinase Saccharomyces cerevisiae S288C