Title : Vascular insulin resistance related to endoplasmic reticulum stress in aortas from a rat model of chronic kidney disease.

Pub. Date : 2012 Nov 1

PMID : 22942179






1 Functional Relationships(s)
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1 Tyrosine phosphorylation of insulin receptor-beta and insulin receptor substrate (IRS)-1 and phosphorylation of protein kinase B and endothelial nitric oxide synthase were all decreased in aorta from RRM rats, whereas serine phosphorylation of IRS-1, a marker of insulin resistance, was increased. Tyrosine insulin receptor substrate 1 Rattus norvegicus