Title : Tobacco nitrosamine N-nitrosonornicotine as inhibitor of neuronal nicotinic acetylcholine receptors.

Pub. Date : 2013 Jan

PMID : 22847530






1 Functional Relationships(s)
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1 NNN-induced inhibition of nicotine-evoked alpha3beta4 nAChR activity was dose-dependent with an inhibitory constant (IC(50)) of 0.92 +- 0.05 mM. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus