Title : Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.

Pub. Date : 2012 Aug 21

PMID : 22846040






3 Functional Relationships(s)
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1 Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 A crystal structure of the N-terminal domain of RSK2 with bound inhibitor. SL0101 ribosomal protein S6 kinase A3 Homo sapiens
2 Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 A crystal structure of the N-terminal domain of RSK2 with bound inhibitor. SL0101 ribosomal protein S6 kinase A3 Homo sapiens
3 Here, we report the crystal structure of the complex of the N-terminal kinase domain of the RSK2 isoform with SL0101 at 1.5 A resolution. SL0101 ribosomal protein S6 kinase A3 Homo sapiens