Pub. Date : 2012 Aug 1
PMID : 22728059
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The purpose of this study was to determine (1) existence of Ang-(1-7) receptor, Mas-R, within the dorsolateral PAG (dl-PAG), (2) the role for Ang-(1-7) in modulating activity of dl-PAG neurons, and (3) the mechanisms by which Ang-(1-7) plays a regulatory role. | dl-pag | angiopoietin 1 | Homo sapiens |
| 2 | The purpose of this study was to determine (1) existence of Ang-(1-7) receptor, Mas-R, within the dorsolateral PAG (dl-PAG), (2) the role for Ang-(1-7) in modulating activity of dl-PAG neurons, and (3) the mechanisms by which Ang-(1-7) plays a regulatory role. | dl-pag | angiopoietin 1 | Homo sapiens |
| 3 | Whole cell patch-clamp recording demonstrated that the discharge rates of dl-PAG neurons were decreased from 4.35+-0.32 Hz of control to 1.06+-0.34 Hz (P<0.05, vs. control) by 100 nM of Ang-(1-7). | dl-pag | angiopoietin 1 | Homo sapiens |
| 4 | Those findings suggest that Ang-(1-7) plays an inhibitory role in the dl-PAG via a NO dependent signaling pathway. | dl-pag | angiopoietin 1 | Homo sapiens |