Title : The role of pathway-selective insulin resistance and responsiveness in diabetic dyslipoproteinemia.

Pub. Date : 2012 Aug

PMID : 22617754






1 Functional Relationships(s)
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1 This new study, in combination with important prior work, provides clues to several long-standing mysteries, such as how AKT might regulate lipid-lowering and glucose-lowering pathways that become insulin-resistant but also lipogenic pathways that remain insulin-responsive, as well as a potential role for NOX4 in insulin-stimulated generation of oxysterol ligands for LXR, a key lipogenic factor. Oxysterols AKT serine/threonine kinase 1 Homo sapiens