Title : Nicotine enhances proliferation, migration, and radioresistance of human malignant glioma cells through EGFR activation.

Pub. Date : 2013 Apr

PMID : 22614999






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Nicotine increased phosphorylation of EGFR(tyr992), AKT(ser473), and ERK. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 It was therefore concluded that nicotine stimulates the malignant behavior of glioma cells in vitro by activation of the EGFR and downstream AKT and ERK pathways. Nicotine AKT serine/threonine kinase 1 Homo sapiens