Title : Uptake routes of tumor-antigen MAGE-A3 by dendritic cells determine priming of naïve T-cell subtypes.

Pub. Date : 2012 Nov

PMID : 22562379






1 Functional Relationships(s)
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1 Induction of CD8(+) T-cell response was favored by stimulating naive T cells with either antibody-opsonized MAGE-A3 protein or with the bortezomib-pretreated U266 cells, indicating that receptor-mediated uptake favors cross-presentation of antigens. Bortezomib CD8a molecule Homo sapiens