Title : Blockade of nicotinic and muscarinic receptors facilitates spontaneous migration of human peripheral granulocytes: failure in cystic fibrosis.

Pub. Date : 2012 Nov 27

PMID : 22525378






2 Functional Relationships(s)
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1 KEY FINDINGS: In the absence of test substances 4900+-1800 (n=10) leucocytes migrated within a time period of 2 h. In the presence of tubocurarine (TC, 30 muM) the cell number increased to 7500+-2700 [n=10] corresponding to an increase of 162+-20% (mean of individual experiments; p<0.02). Tubocurarine latexin Homo sapiens
2 Also in the presence of atropine (1 muM) and TC (30 muM) a significant effect was not detected (5800+-1300 [n=10]). Tubocurarine latexin Homo sapiens