Title : Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.

Pub. Date : 2010 Dec

PMID : 22432562






3 Functional Relationships(s)
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1 Overexpression of p53 mRNA was observed in both cancerous cell lines, but it was differentially altered by folic acid administration in only SCC25 cells. Folic Acid tumor protein p53 Homo sapiens
2 These findings suggest folic acid administration may significantly alter growth of oral cancers in vitro via p53-dependent and p53-independent pathways. Folic Acid tumor protein p53 Homo sapiens
3 These findings suggest folic acid administration may significantly alter growth of oral cancers in vitro via p53-dependent and p53-independent pathways. Folic Acid tumor protein p53 Homo sapiens