Pub. Date : 2012 May
PMID : 22411726
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Digoxin, as a P-glycoprotein (P-gp) substrate, was substantially effluxed in the basolateral to apical direction but inhibited by the three alkaloids. | Alkaloids | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Digoxin, as a P-glycoprotein (P-gp) substrate, was substantially effluxed in the basolateral to apical direction but inhibited by the three alkaloids. | Alkaloids | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | These observations indicated that the three alkaloids may not only be P-gp inhibitors but also its substrates; they interact with each other and can potentially enhance their own bioavailability when taken concomitantly. | Alkaloids | ATP binding cassette subfamily B member 1 | Homo sapiens |