Title : Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors.

Pub. Date : 2013 Apr

PMID : 22299576






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These coumarins thus act as isoform-selective CA inhibitors with the possibility to target isoforms involved in pathologies such as obesity (CA VA/VB) or cancer (CA IX and XII) without inhibiting the physiologically dominant, highly abundant hCA I and II. Coumarins carbonic anhydrase 5A Homo sapiens