Title : The nuclear receptor PPAR╬▓/╬┤ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

Pub. Date : 2011 Dec 15

PMID : 22135324






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Transcriptional profiling revealed that the lactate dehydrogenase b (Ldhb)/Ldha gene expression ratio is increased in MCK-PPARbeta/delta muscle, an isoenzyme shift that diverts pyruvate into the mitochondrion for the final steps of glucose oxidation. Glucose peroxisome proliferator activator receptor delta Mus musculus
2 MCK-PPARbeta/delta muscle was shown to have high glycogen stores, increased levels of GLUT4, and augmented capacity for mitochondrial pyruvate oxidation, suggesting a broad reprogramming of glucose utilization pathways. Glucose peroxisome proliferator activator receptor delta Mus musculus