Title : Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells.

Pub. Date : 2012 Jan 1

PMID : 22064362






1 Functional Relationships(s)
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1 Activation of AMPK, a cellular metabolic sensor, and its downstream target ACC by low glucose concentration was largely inhibited by addition of MnTBAP, a MnSOD and catalase mimetic that also totally suppressed superoxide production. Superoxides superoxide dismutase 2 Rattus norvegicus