Title : Manganese superoxide dismutase inhibits neointima formation through attenuation of migration and proliferation of vascular smooth muscle cells.

Pub. Date : 2012 Jan 1

PMID : 22062629






3 Functional Relationships(s)
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1 Because of its subcellular localization, SOD2 is considered the first line of defense against oxidative stress and plays a central role in metabolizing superoxide. Superoxides superoxide dismutase 2 Rattus norvegicus
2 Because mitochondria are the most important sources of superoxide anion, we speculated that SOD2 may have therapeutic benefits in preventing vascular remodeling. Superoxides superoxide dismutase 2 Rattus norvegicus
3 SOD2 exerts its inhibitory effect on VSMC migration induced by angiotensin II by scavenging superoxide anion and suppressing the phosphorylation of Akt. Superoxides superoxide dismutase 2 Rattus norvegicus