Title : Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.

Pub. Date : 2011 Nov 1

PMID : 21978950






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Utilizing a parallel synthetic approach, 50 various functionalized tetrahydro-beta-carboline derivatives were prepared and assessed for activities related to cancer chemoprevention and cancer treatment: induction of quinone reductase 1 (QR1) and inhibition of aromatase, nitric oxide (NO) production, tumor necrosis factor (TNF)-alpha-induced NFkappaB activity, and MCF7 breast cancer cell proliferation. tryptoline nuclear factor kappa B subunit 1 Homo sapiens