Title : β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.

Pub. Date : 2011 Nov

PMID : 21937717






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 p190RhoGAP is itself activated by Src-dependent tyrosine phosphorylation, which facilitates complex formation with p120RasGAP. Tyrosine Rho GTPase activating protein 35 Mus musculus
2 Expression of an inactive beta3 integrin subunit abolishes p190RhoGAP tyrosine phosphorylation, demonstrating a mechanistic link between beta3 integrin-activated Src and EGFR regulation of the RhoA inhibitor. Tyrosine Rho GTPase activating protein 35 Mus musculus