Title : 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent.

Pub. Date : 2011 Dec

PMID : 21896918






1 Functional Relationships(s)
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1 These results suggest that PPARalpha is activated by increased concentrations of free fatty acids that may arise from impaired fatty acid metabolism caused by altered levels of ATP, AMP, and ZMP after AICAR or adenosine treatment. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus