Title : The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional.

Pub. Date : 2011 Sep 13

PMID : 21876184






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The K(m) for NADPH is similar for both enzymes but DHFRL1 has a higher K(m) for dihydrofolate when compared to DHFR. dihydrofolate dihydrofolate reductase 2 Homo sapiens
2 The localization of DHFRL1 to the mitochondria, as demonstrated by confocal microscopy, indicates that mitochondrial dihydrofolate reductase activity may be optimal with a lowered affinity for dihydrofolate. dihydrofolate dihydrofolate reductase 2 Homo sapiens