Title : Nelfinavir induces radiation sensitization in pituitary adenoma cells.

Pub. Date : 2011 Oct 1

PMID : 21811091






2 Functional Relationships(s)
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1 We evaluated tumor growth delay and confirmed nelfinavir"s effect on the PI3K-AKT-mTOR pathway in a hind-flank model. Nelfinavir mechanistic target of rapamycin kinase Homo sapiens
2 Decreased phospho-S6 on Western blotting in vitro and immunohistochemistry in vivo demonstrated nelfinavir inhibition of the PI3K-AKT-mTOR pathway. Nelfinavir mechanistic target of rapamycin kinase Homo sapiens