Title : Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice.

Pub. Date : 2011 Nov

PMID : 21748763






1 Functional Relationships(s)
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1 Mitochondrial production of superoxide was increased in the jnk2(-/-) and WT mice, compared to the jnk1(-/-) mice, upon pyrazole plus TNF-alpha treatment. Superoxides tumor necrosis factor Mus musculus