Title : Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations.

Pub. Date : 2012 Feb

PMID : 21541746






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Evaluation of the active site residues of the CYP7B1 model and validation of the active site architecture were performed via molecular docking experiments: the docking of the substrates 25-hydroxycholesterol and 27-hydroxycholesterol and the inhibitor 3alpha-Adiol identified structurally and functionally important residues. 27-hydroxycholesterol cytochrome P450 family 7 subfamily B member 1 Homo sapiens