Title : Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition.

Pub. Date : 2011 Sep

PMID : 21484229






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition. nafamostat nuclear factor kappa B subunit 1 Homo sapiens
2 We previously reported that nafamostat mesilate, a synthetic serine protease inhibitor, blocks NF-kappaB activation in pancreatic cancer. nafamostat nuclear factor kappa B subunit 1 Homo sapiens
3 RESULTS: In vitro, nafamostat mesilate inhibited activities of NF-kappaB, phosphorylated IkappaBalpha, ICAM-1, VEGF and MMP-9. nafamostat nuclear factor kappa B subunit 1 Homo sapiens