Title : Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes.

Pub. Date : 2011 Mar 15

PMID : 21211511






1 Functional Relationships(s)
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1 These results provide strong pharmacological and genetic evidence for the implication of H-Ras and NADPH oxidase-generated superoxide production in MMP-13 gene regulation by IL-1beta and TNF-alpha. Superoxides tumor necrosis factor Homo sapiens