Title : Radiation induced non-targeted response: mechanism and potential clinical implications.

Pub. Date : 2011 Jun

PMID : 21143185






1 Functional Relationships(s)
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1 There is recent evidence that the NF-kappaB-dependent gene expression of interleukin 8, interleukin 6, cyclooxygenase-2, tumor necrosis factor and interleukin 33 in directly irradiated cells produced the cytokines and prostaglandin E2 with autocrine/paracrine functions, which further activated signaling pathways and induced NF-kappaB-dependent gene expression in bystander cells. Dinoprostone C-X-C motif chemokine ligand 8 Homo sapiens