Title : Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis.

Pub. Date : 2011 Feb

PMID : 21123734

1 Functional Relationships(s)
Compound Name
Protein Name
1 TNF-alpha rapidly enhanced endogenous CO production in a superoxide- and NADPH oxidase-dependent manner in CMVEC with innate, but not with small interfering RNA (siRNA)-downregulated Nox4 activity. Superoxides tumor necrosis factor Homo sapiens