Title : Experimental varicocele induces p53-dependent germ cell apoptosis through activation of γ-H2AX.

Pub. Date : 2010

PMID : 20530960






2 Functional Relationships(s)
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1 CONCLUSIONS: These results show that experimental varicocele may induce p53-dependent apoptosis through activation of gamma-H2AX in the primary spermatocytes, and suggest that gamma-H2AX may be related to apoptotic signal transduction in experimental varicocele. gamma-h2ax tumor protein p53 Homo sapiens
2 CONCLUSIONS: These results show that experimental varicocele may induce p53-dependent apoptosis through activation of gamma-H2AX in the primary spermatocytes, and suggest that gamma-H2AX may be related to apoptotic signal transduction in experimental varicocele. gamma-h2ax tumor protein p53 Homo sapiens