Title : Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.

Pub. Date : 2010 Jul 9

PMID : 20442405






1 Functional Relationships(s)
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1 Within immortalized MEFs, FAK activity was required for fibronectin-stimulated FAK-p190RhoGAP association and p190RhoGAP tyrosine phosphorylation linked to decreased RhoA GTPase activity, focal adhesion turnover, and directional motility. Tyrosine Rho GTPase activating protein 35 Mus musculus