Title : Recent developments with lipoprotein-associated phospholipase A2 inhibitors.

Pub. Date : 2010 Jan

PMID : 20425270






1 Functional Relationships(s)
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1 Lp-PLA(2) generates two proinflammatory mediators, lysophosphatidylcholine and oxidized nonesterified fatty acids, which play a major role in the development of atherosclerotic lesions and formation of a necrotic core, leading to more vulnerable plaques. Fatty Acids, Nonesterified phospholipase A2 group VII Homo sapiens